- Serum Angiotensin-Coverting Enzyme Levels in Coal Worker's Pneumoconiosis.
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Kyung Dong Kim, Myung Sook Choi, Chae Hoon Lee, Chung Sook Kim, Eun Kyung Bae
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Yeungnam Univ J Med. 1989;6(1):109-119. Published online June 30, 1989
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DOI: https://doi.org/10.12701/yujm.1989.6.1.109
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- We measured fasting Serum Angiotensin-Converting Enzyme (SACE) in 100 healthy controls and 75 coal worker's pneumoconiosis (CWP) patients by a commercial kits (ACEcolor®, Fujirio Inc., Japan) and evaluated this manual method. The linear range extends to an activity of 80U/L. Precision on a commercial control serum (ACE control-N®, Sigma Co.) with a mean value of 9.47U/L yielded a within-run and between-run CVs are 5.6% (N=15) and 6.9% (N=14) respectively. Save in 75 CWP was 20.3±5.7U/L (mean±s.d.); higher than in healthy controls (13.4±3.9U/L, P<0.01). No correlation was found between SACE, sex, and age. The results suggest that the measurement for SACE and follow-up SACE in coal workers may be a useful diagnostic tools for CWP.
- Extra-LDH Isoenzyme(LD₆) in Myocardial Infarction with Serious Course: Two cases report.
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Kyung Dong Kim, Myung Sook Choi, Chae Hoon Lee, Chang Ho Jeon, Chung Sook Kim, Young Jo Kim
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Yeungnam Univ J Med. 1988;5(2):247-254. Published online December 31, 1988
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DOI: https://doi.org/10.12701/yujm.1988.5.2.247
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- Serum lactate dehydrogenase isoenzyme are separated 5 fractions (LD1-LD5) in normal serum by agarose electrophoresis. An unusual band on the cathodic side of LD5 isoenzyme has been found on lactate dehydrogenase electrophoresis is of serum, called LD6, and the presence of which signifies a poor prognosis for the patients of myocardial infarction. In recent, we have experienced LD6 in two patients with myocardial infarction. Cardiac arrest was noted within 24 hours after exhibition of LD6 extra band and they did not recover from their illness.
- A Case of Pure Red Cell Aplasia.
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Myung Sook Choi, Chae Hoon Lee, Chang Ho Cheon, Kyung Dong Kim, Chung Sook Kim, Myung Soo Hyun
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Yeungnam Univ J Med. 1988;5(2):239-246. Published online December 31, 1988
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DOI: https://doi.org/10.12701/yujm.1988.5.2.239
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- Pure red cell aplasia in uncommon disorder characterized by finding of anemia, absence of nucleated red blood cell in the marrow, absence of reticulocytes in the peripheral blood and normal peripheral platelet and leukocytes counts. We experienced one case of pure red cell aplasia associated with hemolytic anemia characterized by hemoglobinuria, reticulocytopenia, and erythroid hypoplasia of the bone marrow. The cause of the illness was not definitely identified, but we concluded that this patient had simultaneous occurrence of PRCA and hemolytic anemia following administration of diphenylhydantoin after craniotomy rather than virus or bacteria induced. The simultaneous occurrence of PRCA and hemolytic anemia in uncommon and the mechanism for diphenylhydantoin induced PRCA and hemolytic anemia is unclear.
- Analysis of the Results of Blood Cultures, 1984~1987 at Yeungnam University Hospital.
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Chung Sook Kim, Chae Hoon Lee, Myung Sook Choi, Chang Ho Cheon, Kyung Dong Kim
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Yeungnam Univ J Med. 1988;5(1):49-60. Published online June 30, 1988
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DOI: https://doi.org/10.12701/yujm.1988.5.1.49
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- Reviewing the results of the blood cultures performed at Yeungnam University Hospital during 4-year-period through January, 1, 1984 to December 31, 1987, the following results were obtained. 1) Out of 8083 blood specimens cultured microorganisms grew in 582 specimens with positivity rate of 7.20%. Polymicrobial bacteremia was found in 16 patients. 2) Among 582 positive specimens, Gram-positive cocci grew in 189 specimens, and Gram-negative bacilli, in 393 specimens. Clinically significant microorganisms consisted of 82 Staphylococcus aureus, and 20 Streptococcus species in Gram-positive cocci group, 80 Salmonella typhi, 72 Escherichia coli, 72 Salmonella paratyphi A in Enterobacteriaceae, and 46 Pseudomonas cepacia, and 16 Pseudomonas aeruginosa in glucose non-fermenting microorganisms. 3) Increasing incidence of Serratia, Acinetobacter and Pseudomonas species as major nosocomial infection source is noteworthy. They showed increased tendency from 6.3% of 1984 to 17.7% of 1987 of total positive blood cultures. 4) High isolation rate of Pseudomonas species and Aeromonas hydrophila was noted in summer, while Salmonella typhi showed high prevalence from May to September and in January. 5) In susceptibility tests of isolated organisms, staphylococcus aureus was sensitive to basic antimicrobial agents except for ampicillin. The glucose non-fermenting microorganisms showed high resistance to basic antimicrobial agents in 32.2%. In conclusion, considering the relatively higher incidence of growth of Staphylococcus epidermidis than ideal level indicates that sampling technique should be improved. Secondly, all the hospital staffs in cooperation with Hospital Infection Committee are desirable to pay efforts to decrease the nosocomial infection.
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